Enzymatic Degradation of Sequential Polymers Containing a Tripeptide Sequence L-Alanine–L-Leucine–γ-Ethyl L-Glutamate and an α-Hydroxy Acid L-Lactic Acid or α-Amino Acid L-Alanine
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چکیده
منابع مشابه
Enzymatic synthesis of DNA strands containing α-L-LNA (α-L-configured locked nucleic acid) thymine nucleotides
We describe the first enzymatic incorporation of an α-L-LNA nucleotide into an oligonucleotide. It was found that the 5'-triphosphate of α-L-LNA is a substrate for the DNA polymerases KOD, 9°N(m), Phusion and HIV RT. Three dispersed α-L-LNA thymine nucleotides can be incorporated into DNA strands by all four polymerases, but they were unable to perform consecutive incorporations of α-L-LNA nucl...
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Most of the L-a-hydroxy acid oxidase in Tetrahymena is localized on a particulate fraction (4) whose sedimentation properties differ from those of lysosomes and mitochondria (1). The association of this enzyme (or family of enzymes; see reference 3) with -amino acid oxidase and catalase in density gradient centrifugation has provided evidence for the existence of peroxisomes in Tetrahymena (1, ...
متن کاملl-Hydroxy acid oxidase.
In previous communications (l-4) the properties and isolation of the l-amino acid oxidase of rat kidney were described. Quite accidentally, it was found that solutions of the enzyme were able to catalyze the oxidation of Z-hydroxy acids, and further study disclosed that this ability ran parallel with l-amino acid oxidase activity from the first crude extract to the final electrophoretically hom...
متن کاملAn L-threonine transaldolase is required for L-threo-β-hydroxy-α-amino acid assembly during obafluorin biosynthesis
β-Lactone natural products occur infrequently in nature but possess a variety of potent and valuable biological activities. They are commonly derived from β-hydroxy-α-amino acids, which are themselves valuable chiral building blocks for chemical synthesis and precursors to numerous important medicines. However, despite a number of excellent synthetic methods for their asymmetric synthesis, few ...
متن کاملIn Vitro Degradation of Poly (L-co-D,L lactic acid) Containing PCL-T
The application of polymer-based bioresorbable temporary devices in the medical field grows continuously, and professionals from several areas act to solve problems related to body functions lost due to diseases, accidents or natural wear. Here we study the influence from poly(caprolactonetriol) (PCL-T) on the degeneration process in the copolymer poly(L-co-DL-lactic acid) (PLDLA) membrane, by ...
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ژورنال
عنوان ژورنال: Polymer Journal
سال: 1988
ISSN: 0032-3896,1349-0540
DOI: 10.1295/polymj.20.281